COVID-19: Sree Chitra’s unique take a look at kit space to carry pattern-to-end result time below two hours

The group which developed the technology

By Relate Facts Provider

THIRUVANANTHAPURAM: Revolutionising the Covid-19 screening in the country, the Sree Chitra Tirunal Institute for Scientific Sciences and Know-how (SCTIMST) has developed a take a look at kit that can diagnose the disease in a single take a look at at a whimsical lower fee.

The take a look at kit — Chitra GeneLAMP-N — now awaits the approval of Indian Council for Scientific Analysis (ICMR) for Covid19 sorting out in India and licence from Central Treatment Usual Retain watch over Organisation (CDSCO) for manufacturing.

Anoop Thekkuveettil

“ICMR had permitted the Nationwide Institute of Virology (NIV), Alappuzha, to validate the tests and the CDSCO had supplied licence for the the same. The take a look at at NIV stumbled on that Chitra GeneLAMP-N showed 100 per cent accuracy and congruence with the RT-PCR outcomes,” said SCTIMST director Asha Kishore.

The kit detects the N Gene of SARS-CoV-2 utilizing reverse transcriptase loop-mediated amplification of viral nucleic acid.  “Using Chitra GeneLAMP-N, gene detection would be performed in 10 minutes and the pattern-to-end result time (from RNA extraction in swab to RT-LAMP detection time) will likely be no longer up to two hours,” said Asha. 

30 samples would be examined in a single batch

“Thirty samples would be examined in a single batch in a machine and the vastly lower machine waiting time will enable an most attention-grabbing preference of samples to be examined day after day in a single machine in a pair of shifts. The sorting out facility would be space up with out anxiousness, even in the laboratories of district hospitals,” said Asha. The outcomes would be read from the machine by noting the commerce in fluorescence.

SCTIMST has also developed the explicit RNA extraction kits alongside with GeneLAMP-N take a look at kits and the sorting out system. The analysis and pattern of Chitra GeneLAMP-N were fully funded by the Division of Science and Know-how.

The technology has been transferred to M/S Agappe Diagnostics Ltd, Ernakulam — a partner of the institute in the section of in-vitro diagnostics — for make. It took ultimate three weeks for the group led by the senior scientist Anoop Thekkuveettil of the institute’s Biomedical Know-how Soar to manufacture the kit. The the same group had earlier developed a take a look at kit and a highly sensitive system utilizing the LAMP system for the detection of DNA of mycobacterium tuberculosis (TB) from sputum samples of patients with suspected lung TB in 2018-2019.

Awaiting  ICMR nod

Chitra GeneLAMP-N now awaits ICMR acclaim for Covid-19 sorting out in India

It took ultimate three weeks for the group led by senior scientist Anoop Thekkuveettil  to manufacture the kit

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